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22 Share capital continued ; Share options The Company encourages employee participation in its shares through ownership and continues to operate various Share Option Schemes and the Unapproved Share Option Scheme. Under the terms of these Schemes the Board may offer options to purchase Ordinary Shares in the Company to employees, including Directors, at a price not less than the higher of the nominal value and the market value of the shares on the date of grant. Options granted to UK and European employees are only exercisable between the third and tenth anniversary of the date of grant, and are subject to the Company's Code of Conduct for dealing in Shares, and the Model Code. Options granted to US employees prior to 2001 vest at 25% per annum from the date of grant and there were no performance criteria. UK and European options granted prior to 2001 may only be exercised if the growth in the Company's share price over a consecutive three-year period exceeds the growth over the same period in the FT-SE All Share Index. This criteria was satisfied for the first time in March 2000. Employees with options that are within their exercise period are now able to exercise those options within any one-year period from the date the performance condition is satisfied. Super Options are exercisable after five years and are subject to higher performance conditions in accordance with those recommended by the Association of British Insurers. Following changes to the option plans approved at the Annual General Meeting in June 2001, options granted to Directors and senior employees since that date are subject to performance conditions linked to the total shareholder return of a comparator group of companies, and are not subject to retesting. Options granted to other US employees continue to vest at 25% per annum with no performance criteria, and other European employees who are not Directors or senior employees can exercise their options after three years and are not subject to performance conditions. The Group's plans are further detailed in the Remuneration Report. The following table summarises the activity in share options for the years to 31 December 2002 and 31 December 2003 and amoxil.

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Fact that they can no longer do their work without digital tools, and we're in the infancy of that. It's only a matter of time, just like the old debate decades ago of whether or not it's appropriate for students to take a calculator into a math exam. They'll forget their multiplication tables if they don't, as if that was critically important. And of course we're past that, and now of course you wouldn't do calculus or anything else without a good, advanced calculator. It's a matter of time before we're bringing our loaded PDAs into our board exams. After all, our ability to manage knowledge is more important than our ability to remember a certain minutiae. This quote, by the way, I got out of a book. The real pioneer of this whole concept was Michael Millensen, who in 1997 published a book called Demanding Medical Excellence. Millenson is a health reporter for the Chicago Tribune, and he got a fellowship from RWJ to study knowledge management in medicine for a year and publish basically a very conclusive written report that states the only way to achieve medical excellence is through the use of information technology and medicine, because birth control pills effective.