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Competitive market forces that exist in the pharmaceutical industry are the best insurance against excessive drug prices and a key driver of continued discovery and development of innovative drugs that help patients. We believe that integrated, private-sector coverage for drugs is the best way to ensure access by all patients to the miracles of modern medicines. Counterfeiting In the past few years, the prescription pharmaceutical counterfeiting business has evolved into a highly sophisticated, global endeavor, encompassing specialized distribution syndicates that deliver authenticlooking counterfeit tablets, packaging, and labels through both regulated and unregulated channels-- including products imported from one country to another through the Internet. Counterfeit drugs are manufactured illegally in unsanitary conditions and might include too little, too much, or no active ingredients, or harmful ingredients. All counterfeit drugs pose a public health risk. Lilly remains committed to patient safety, and the company's global anti-counterfeiting efforts are an important component of our concern for public health. Lilly is intent on being a leader in combating pharmaceutical counterfeiting and has initiated a broad range of actions, including the addition of enhanced anti-counterfeiting technologies for Lilly products and packaging, and changes in our distribution system. Lilly is also partnering with governments, nongovernmental organizations, and trade associations to strengthen, enact, and enforce anti-counterfeiting laws, and to raise awareness. Lilly is aggressively pursuing and litigating against those who manufacture and market counterfeit medicines. These steps against the exploitive actions of these counterfeiters are designed to help protect the patients who place their trust in our company and its products. Value of Pharmaceuticals Lilly advocates policies that recognize the value of pharmaceuticals in treating patients and reducing total health care costs. In many instances, pharmaceuticals eliminate the need for surgery and hospitalization, slow or reverse the progress of a disease, prevent a disease from developing, and allow people to return to work sooner. With the U.S., for example, devoting approximately 15 percent of its economy to health care as measured by gross domestic product ; , there is increasing pressure to contain growth in these costs. Innovative and cost-effective pharmaceuticals are an important, for instance, eltroxin.
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The most important determinant is viral load. Ideally, viral load should be below the limits of quantitation of clinically available assays generally less than 500 HIV-1 RNA copies mL ; . If after 46 months the viral load has not decreased below 500 copies mL, therapy may be continued if other therapeutic options are not available or the initial viral load was high enough that it limited an optimal response. These patients should be monitored closely. An increase in viral load after an initial decline to undetectable levels warrants close observation and consideration of treatment alteration. A viral load greater than 500010 000 HIV-1 RNA copies mL indicates treatment failure and the need to change therapy. Therapy should be altered if there is evidence of intolerance to the medication or of major toxic effects. Immunologic decrease in CD4 count ; , clinical or virologic progression should prompt consideration of a change in therapy.
Notes: aOther names include Levothroid, Eltroxin, L-Thyroxine, Levotabs, Levoxyl, Levo-T, Unithroid. bOther names include Maxidone, Anexsia, Bancap HC, Lorcet, Lorcet Plus, Lortab, Zydone. cBenzodiazepines are excluded from payment under Medicare Part D but may still be covered under Medicaid with federal match. dSustained release SR ; or controlled release CR ; formulation remains under patent. Other forms available as generic.
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